Description: Macintosh HD:Users:ynahmias:Desktop:Awesome Photos:Koby HR 2.jpgYaakov Nahmias


Professor of Bioengineering


Office: 3-512 Silberman Institute (ASILS)

Phone: +972-2-5494640








B.Sc., Chemical Engineering, Technion, Israel Institute of Technology, 1999

Ph.D., Biomedical Engineering, University of Minnesota, 2004

Postdoc, Bioengineering, Harvard Medical School, 2006




Yaakov "Koby" Nahmias is an ERC-funded biomedical engineer and entrepreneur. He is the founding director of the Alexander Grass Center for Bioengineering at the Hebrew University of Jerusalem and the co-founder of the Israeli BioDesign program. Nahmias work is focused on the integration of tissue engineering, microfluidics, and metabolic regulation.


Selected Publications


Goggle Scholar: H-Index 30, Citation 3763

 OCRID: 0000-0002-6051-616X

 Complete List of Published Work in MyBibliography


1               Y. Nahmias, D. J. Odde, Micropatterning of living cells by laser-guided direct writing: application to fabrication of hepatic-endothelial sinusoid-like structures, Nature Protocols, 1(5):2288-2296(2006)

2               O. Benny, O. Fainaru, A. Adini, F. Cassiola, L. Bazinet, I. Adini, E. Pravda, Y. Nahmias, S. Koirala, G. Corfas, R. J. D'Amato, J. Folkman, An orally delivered small-molecule formulation with antiangiogenic and anticancer activity, Nature Biotechnology. 26(7):799-807 (2008)

3               S. Kidambi, R. Yarmush, E. Novik, P.B. Chao, M.L. Yarmush, Y. Nahmias, Oxygen-mediated enhancement of metabolism, functional polarization, gene expression, and drug clearance in co-cultures of primary hepatocytes, PNAS 106(37):15714-9 (2009)

4               B. Uygun, A. Soto-Gutierrez, H. Yagi, M.L. Izamis, M.A. Guzzardi, C. Shulman, J. Milwid, N. Kobayashi, A. Tilles, F. Berthiaume, M. Hertl, Y. Nahmias, M.L. Yarmush, K. Uygun. Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix. Nature Medicine. 16(7):814-20. (2010)

5               P. Koria, H. Yagi, Y. Kitagawa, Z. Megeed, Y. Nahmias, R. Sheridan, M.L. Yarmush, Self-assembling elastin-like peptides growth factor chimeric nanoparticles for the treatment of chronic wounds. PNAS. 108(3):1034-9 (2011)

6               Y. Avior, G. Levy, M. Zimerman D. Kitsberg, R. Schwartz, R. Sadeh, A. Moussaieff, M. Cohen, J. Itskovitz-Eldor, Y. Nahmias. Microbial-Derived Lithocholic Acid and Vitamin K2 Drive the Metabolic Maturation of Pluripotent Stem Cells Derived Hepatocytes. Hepatology 2(1): 265-78. (2015)

7               A. Moussaieff, M. Rouleau, D. Kitsberg, M. Cohen, D. Barasch, A. Nemirovski, S.S. Shen-Orr, I. Laevsky, M. Amit, D. Bomze, B. Elena-Herrmann, T. Scherf, M. Nissim-Rafinia, S. Kempa, J. Itskovitz-Eldor E. Meshorer, D. Aberdam, Y. Nahmias. Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells. Cell Metabolism 21(3): 392-402. (2015)

8               G. Levy, D. Bomze, S. Heinz, S.D. Ramachandran, A. Noerenberg, M. Cohen, O. Shibolet, E. Sklan, J. Braspenning, Y. Nahmias. Long-term culture and expansion of primary human hepatocytes. Nature Biotechnology 33(12): 1264-1271. (2015)

9               D. Bavli, S. Prill, E. Ezra, G. Levy, M. Cohen, M. Vinken, J. Vanfleteren, M. Jaeger, Y. Nahmias, Real-time monitoring of metabolic function in liver-on-chip microdevices tracks the dynamics of mitochondrial dysfunction. PNAS 113(16):E2231-40. (2016)

10           G. Levy, M.A. Guzzardi, N. Habib, D. Kitsberg, D. Bomze, B.E. Uygun, K. Uygun, M. Trippler, J.F. Schlaak, O. Shibolet, E.H. Sklan, M. Cohen, J. Timm, N. Friedman, Y. Nahmias, Nuclear Receptors Control Pro- and Anti-Viral Metabolic Response to HCV Infection. Nature Chemical Biology 12, 1037–1045 (2016)