Fluoroscopy-based navigation in computer-aided orthopaedic surgery L. Joskowicz School of Computer Science and Engineering, The Hebrew Universtity of Jerusalem, ISRAEL Abstract: We present a summary of the state of the art of fluoroscopy-based systems in computer-aided orthopaedic surgery (CAOS). The goal of CAOS is to improve the surgeons' performance in surgeries where intraoperative X-ray fluoroscopic images are pervasive. The systems include a real-time tracking device, a computer with image processing and visualization software, a fluoroscope connected to the computer via a video frame grabber, and optionally a robot. We first motivate the need for CAOS systems and describe the general principles of fluoroscopy-based navigation. We then describe four classes of systems: (1) CT based systems, (2) fluoroscopy-based systems, (3) CT and fluoroscopy-only systems, and (4) systems combining fluoroscopy and surgical robots. We describe the technical principles of each, evaluate their pros and cons, and conclude with perspectives. Keywords: medical systems, medical applications, image registration, tracking systems, robotics, navigation systems. Published in: Proc. of the IFAC Conf. on Mechatronics Systems, Darmstadt, Germany, 2000, Isermann et. al. editors, Elsevier, 2000, pp 235--241.