Computer-assisted image-guided intramedullary nailing of femoral shaft fractures Eric J. Hazan (1) and Leo Joskowicz (2) (1) División de Traumatología, Hospital de Ortopedia, Centro Nacional de Rehabilitación Ave. Mexico-Xochimilco 289, Mexico 14389 DF, Mexico. (2) School of Computer Science and Engineering, The Hebrew University of Jerusalem, Abstract Closed reduction and intramedullary nailing under X-Ray fluoroscopy is the current treatment of choice for femoral shaft fractures. However, many images are required to successfully perform the procedure, especially for distal locking of the nail, resulting in cumulative radiation exposure to the surgeon. Recently, computer-based technologies have been developed for surgical navigation, enabling the surgeon to accurately track in real-time the instruments, implants and patient anatomy during a procedure. This paper reviews the principles and potential benefits of computer-aided image-guided surgery for femoral shaft fracture, its indications, and its pitfalls. The existing systems - commercially available and prototypes - and the early clinical experience using this technique are also briefly discussed. Keywords: computer-assisted orthopaedic surgery, image-guided surgery, femur fracture, intramedullary nailing. Published in: Techniques in Orthopaedics, Special Issue on Computer-Aided Orthopaedic Surgery, E. Hazan editor, Lippincott, Williams and Wilkens, Philadelphia, USA, Vol. 18(2), 2003, pp 191--201.