Seminar in Bioinformatics

Seminar in Computational Biology Research

Format

* Meetings: on Sundays 15:00-16:45, Ross 224
* Each meeting will discuss a topic. This will include research & review papers on the same topic.
* A pair of the students will prepare the discussion on the paper. These students will present the problem, methods, and results described in the paper and will lead the discussion on the paper.
* The students will also prepare a one-page abstract with the ‘highlights’ of the talk (+ references) that will be published on the seminar website before the talk.
* The students who are presenting the topic are responsible for having a copy of the paper on the website a week in advance, and a copy of the presentation after it was presented.
* Some “Kibud” is in the responsibility of the following week’s students. Hot water will be available.

Grade

* Based on participations in meetings, discussion, the abstract, and the prepared presentation of the papers.Meeting schedule

Schedule

Date	Student	Guide	Topic	Resources*
6/3	Uri H.	Eilon/Elad	Sequence comparison	Bejerano G et al. Shabalina SA et al. Eddy SR Abstract Presentation
13/3	Sofia L. & Nir L.	Gila/Tommy	Comparative genomics	Salzberrg SL Kellis M et al. Kamvysselis M et al. Gasch AP et al. Abstract Presentation extra reading: Genes Genomes and the Road to Diversity
20/3	Dina M.	Gali Niv	Functional genomics	Eisenberg D Marcotte EM Yanai I von Mering C Abstract Presentation
3/4	Ariel T. & Ayelet H.	Eyal	Protein-protein interactions	Legrain P, Trends Genet 2001 von Mering, Nature 2002 Tong AH, Science 2002 Jansen R, Science 2003 Abstract Presentation extra reading: What is Bayesian Statistics, S Eddy, Nat. Bio. 2004 Introduction To Bayesian Networks, O Mosinzon
10/4	Efrat M. & Tali G.	Noa	Gene expression	Eisen MB et al, Proc Natl Acad Sci U S A 1998 Spellman PT et al, Mol Biol Cell 1998 Gasche AP et al, Mol Biol Cell 2000 Ihmels J et al, Nat Genet 2002 Abstract Presentation
1/5	Lior & Ohad M.	Tommy	Motif search	Wasserman WW et al, Nat Rev Gene 2004 Tavazoie S et al, Nat Genet 1999 Beer MA et al, Cell 2004 Pilpel Y et al, Nat Genet 2001 Abstract Presentation
8/5	Azari M.	Shlomit	Transcriptional regulation (location analysis)	Euskirsch G et al, Nat Genet 2004 Ren B et al, Science 2000 Harbison CT et al, Nature 2004 Abstract Presentation
15/5	Saar G.	Tommy	Histone Modifications	Bernstein BE et al. Kurdistani SK et al. Strahl BD, Allis CD Abstract Presentation extra reading: Experimental Annotation of The Human Genome Using Microarrays Technologies, Shoemaker D.D. et al.,Nature 2001 Gena Quantification using Real Time Quantitve PCR, Ginzinger D.B., Exp. Hem., 2002 Dark Matter In The Genome, Johnson J.M., Trends, 2005
6/6 10-12 am	David B.	Zohar	High-throughput Proteomics	Huh WK et al. Ghaemmaghami S et al. Beyer A et al. Phizicky E et al. Abstract Presentation
5/6	Asaf P.	Hanah	Protein structure prediction	Schonbrun J. et al, Struc. Biol. 2002 Jones DT, J Mol Bio 1999 Jones DT, GenTHREADER, J Mol Bio 1999 Abstract Presentation

* Bold text - Mandatory reading material

Seminar in Computational Biology Research

Format

Grade

Schedule

Date

Student

Guide

Topic

Resources*